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Progress in targeted therapy for esophageal cancer

Esophageal Cancer   Issue: 2025 01期 Page: 80-88 Publish Date: 2025/01/28

Title:

Title:

Progress in targeted therapy for esophageal cancer

Author(s):

Author(s):

Xiyao Yin ,Tao Chen ,Jiayi Li ,Pan Chen ,Linlin Shi* and Shegan Gao*

Henan Key Laboratory of Microbiome and Esophageal Cancer Prevention and Treatment, Henan Key Laboratory of Cancer Epigenetics, Cancer Hospital, The First Affiliated Hospital (College of Clinical Medicine) of Henan University of Science and Technology, Luoyang 471003, China

Keywords:

Keywords:

Esophageal cancer ; Targeted therapy ; Epidermal growth factor receptor ; Vascular endothelial growth factor

CLC:

CLC:

DOI:

DOI:

Abstract:

Abstract:

Esophageal cancer is one of the most common aggressive malignant tumors in the digestive system, with a serious epidemiological situation and a poor prognosis. The early diagnosis rate of esophageal cancer is low, and most patients with esophageal cancer are diagnosed with advanced stage. Multiple multimodal-treatments have gradually developed into the most commonly adopted approaches for esophageal cancer, including surgery, chemotherapy, radiotherapy, targeted therapy, and immunotherapy. The emergence of targeted therapy has greatly improved the survival rate of patients with esophageal cancer. This review summarizes the recent progress of targeted therapy in esophageal cancer, discusses the efficacy and safety of relevant drugs, summarizes the relevant important clinical trials, and attempts to provide insights into therapeutic strategies for esophageal cancer.

References:

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